Anti-inflamatórios não esteroides afetam as respostas ao treinamento resistido em indivíduos idosos e de meia-idade?
DOI:
https://doi.org/10.33233/rbfex.v19i6.4406Palavras-chave:
anti-inflamatórios não esteroides; treinamento de resistência; hipertrofia; força muscular; envelhecimentoResumo
Introdução: Os anti-inflamatórios não esteroides (AINEs) estão entre os medicamentos mais populares do mundo para o tratamento da dor e inflamação. Embora o uso a longo prazo de AINEs esteja associado a efeitos adversos renais, cardiovasculares, hepáticos e outros, também foi sugerido que ele pode causar comprometimento nas adaptações neuromuscular promovida pelo exercício. Objetivo: O objetivo desta revisão sistemática foi comparar os efeitos do uso de AINEs nas adaptações neuromusculares, como hipertrofia e força muscular em pessoas de meia-idade e idosos praticantes de treinamento resistido. Métodos: As bases de dados pesquisadas incluíram Bireme, Pubmed e Science Direct. As meta-análises foram conduzidas usando o método de estimativa de variância robusta de efeitos correlacionados com ajustes de pequenas amostras. Resultados: Seis estudos foram incluídos para análise meta-analítica, nenhuma diferença estatística foi encontrada para hipertrofia (ES: 0,000531 ± 0,0424, IC 95%: -0,123 - 0,124; P = 0,991) e força muscular (ES: 0,323 ± 0,213, 95% CI: -0,417 - 1,06; P = 0,258). Conclusão: Os achados desta revisão não sustentam a hipótese de que o uso de AINEs combinado com exercícios resistidos, influencie negativamente a hipertrofia e a força muscular.
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