Evaluation of serum arginase in overweight women under the acute effect of physical exercise - exploratory study
DOI:
https://doi.org/10.33233/rbfex.v20i3.4550Keywords:
obesity; physical exercise; arginaseAbstract
Introduction: Obesity is a multifactorial condition related to the increase of serum arginase, favoring endothelial dysfunction. Physical exercise is a protective factor for endothelial homeostasis. Thus, knowing whether the level of arginase is modified by a physical exercise session is important. Objective: To verify the level of arginase in women with excess weight before and after a physical exercise session and evaluate the association between the level of arginase and the BMI of these patients. Methods: Exploratory study, which used the serum bank of a randomized clinical trial, in which sedentary women 18 to 30 years old, BMI > 24.9 kg/m² were included. Women with diseases that could alter the levels of arginase were excluded. The volunteers were randomized to the intervention group - a light intensity exercise session (EG) and a control group (CG). The serum arginase of 11 women in the CG and 9 in the EG was measured before and 24h after the intervention. Data analysis was performed using the SPSS 20 program using the unpaired Student's t-test and the Mann–Whitney U test. Statistical significance is defined as p < 0.05. Results: The patients' BMI was = 29 ± 4.7 kg/m². The intra-group analysis showed no variation in serum arginase before and after the intervention, as well as in the intergroup comparison using the arginase delta. There was no correlation between the level of arginase and BMI. Conclusion: A session of physical exercise did not change the levels of serum arginase in overweighted women.
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