Acute effects of blood flow restriction resistance exercise on endothelial function and platelet aggregation
DOI:
https://doi.org/10.33233/rbfex.v21i1.4982Keywords:
oxyhemoglobin; deoxyhemoglobin; muscle strength; resistance exercise; hemodynamicsAbstract
Objective: To compare endothelial function and platelet aggregation after resistance exercise performed with low-intensity blood flow restriction (LI-BFR) or free blood flow (LI-FreeBF) and high intensity with no blood flow restriction (HI-FreeBF) in healthy adults. Methods: Ten healthy men (23 ± 3 years) performed three experimental trials involving bilateral leg press and knee extension in a randomized crossover design: LI-BFR (3 x 15 reps at 30% 1 RM), LI-FreeBF (3 x 15 reps at 30% 1 RM), and HI-FreeBF (3 x 8 reps at 80% 1RM). BFR was maintained at 50% of the individual total occlusion pressure during the three sets, and it was released after the end of set 3. Brachial artery flow-mediated dilation (FMD) was measured with ultrasound with Doppler before and after exercise. Blood was collected to determine nitrite levels and platelet aggregation. Results: None of the volunteers reported any adverse reactions during the exercise protocols. A 3 x 2 ANOVA with repeated measures in both factors (condition vs. time) indicated no significant main effects or interactions for FMD, basal and peak brachial artery diameter, and shear rate. Plasma nitrite levels and platelet aggregation did not differ among the three exercise conditions nor pre-post resistance exercise. Conclusion: Our results indicate that lower limbs resistance exercise performed at low or high intensities and with or without BFR does not affect endothelial function, nitrite levels, and platelet aggregation. These findings indicate that such exercise conditions do not seem to represent cardiovascular risk from a hemostatic point of view in healthy adult men.
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