Acute inflammatory responses to high-intensity versus moderate-intensity exercise in young men: a systematic review
DOI:
https://doi.org/10.33233/rbfex.v21i1.5096Abstract
Background: Physical exercise has considerable effects on inflammation markers. Objective: The aim of this review was to compare the acute effects of high-intensity exercise and moderate-intensity exercise on inflammation in young men. Methods: A search was conducted in the Medline/Pubmed, Embase, Cochrane Library, Lilacs/BVS and Web of Science databases and completed in July 2021. Studies were eligible if they met the predefined inclusion criteria: a) randomized clinical trials and quasi-experimental studies; b) conducted on active young men (15 to 24 years old); c) written in Portuguese, English or Spanish; d) applying intense and/or moderate physical exercise protocols. The search strategy was built with the following descriptors: “young adult”, “exercise”, “high-intensity interval training”, and “inflammation”. The specific components examined included circulating levels of cytokines IL-6, IL-10, IL-1β, and TNF-α. The risk-of-bias in the results of the studies was assessed with the tools Rob 2 and ROBINS-I. Results: From the 1417 records identified, 5 studies were selected for analysis (n = 96). Most studies showed a high risk-of-bias. Conclusion: The results suggested an increase in the acute inflammatory response, regardless of exercise intensity. It is assumed that the inflammatory response may also have been influenced by the duration and type of exercise. Further research is needed to examine the impact of exercise intensity on inflammation.
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