Blood pressure response to dynamic resistance exercise with different times under blood flow restriction on normotensive subjects: a randomized crossover trial
DOI:
https://doi.org/10.33233/rbfex.v21i4.5247Keywords:
resistance training, blood flow restriction therapy, blood pressureAbstract
Introduction: Recommendations for time under blood flow restriction (BFR) during resistance training (RT) vary between 5 to 10 minutes, and beneficial effects on muscle mass and strength have already been reported. However, there exists the potential for longer times under restriction to produce greater acute activation of the exercise pressor reflex and subsequent sympathetic pathways leading to a greater hemodynamic response. Objective: To verify blood pressure responses to dynamic resistance exercise with different times (5 vs. 10 minutes) under blood flow restriction in normotensive subjects. Methods: In a randomized crossover trial design, twelve healthy and physically active male participants completed a training with BFR under the following protocols: control, BFR-5 minutes, BFR-10 minutes. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) measurements were taken by an experienced researcher immediately after each exercise set. Results: Both BFR-5 minutes and BFR-10 minutes induced acute elevations in SBP, DBP and heart rate (HR) as the sets progressed, without statistical differences between them. However, BFR-10 displayed a superior effect size for SBP and DBP compared to BFR-5 minutes. Conclusion: Based on the present study results, the time under BFR during resistance exercise does not affect blood pressure response in normotensive subjects.
References
Hughes L, Paton B, Rosenblatt B, Gissane C, Patterson SD. Blood flow restriction training in clinical musculoskeletal rehabilitation: a systematic review and meta-analysis. Br J Sports Med 2017;51(13):1003-11. doi: 10.1136/bjsports-2016-097071
Centner C, Wiegel P, Gollhofer A, Konig D. Effects of blood flow restriction training on muscular strength and hypertrophy in older individuals: a systematic review and meta-analysis. Sports Med 2019;49(1):95-108. doi: 10.1007/s40279-018-0994-1
Lixandrão ME, Ugrinowitsch C, Berton R, Vechin FC, Conceição MS, Damas F, et al. Magnitude of muscle strength and mass adaptations between high-load resistance training versus low-load resistance training associated with blood-flow restriction: a systematic review and meta-analysis. Sports Med 2018;48(2):361-78. doi: 10.1007/s40279-017-0795-y
Spranger MD, Krishnan AC, Levy PD, O'Leary DS, Smith SA. Blood flow restriction training and the exercise pressor reflex: a call for concern. Am J Physiol Heart Circ Physiol 2015;309(9):H1440-1452. doi: 10.1152/ajpheart.00208.2015
Domingos E, Polito MD. Blood pressure response between resistance exercise with and without blood flow restriction: A systematic review and meta-analysis. Life Sci 2018;209:122-31. doi: 10.1016/j.lfs.2018.08.006
Manini TM, Clark BC. Blood flow restricted exercise and skeletal muscle health. Exerc Sport Sci Rev 2009;37(2):78-85. doi: 10.1097/JES.0b013e31819c2e5c
Cuyul-Vasquez I, Leiva-Sepulveda A, Catalan-Medalla O, Berrios-Contreras L. Blood flow restriction training for people with cardiovascular disease: An exploratory review. Rehabilitacion (Madr) 2020;54(2):116-27. doi: 10.1016/j.rh.2020.01.005
Wong V, Song JS, Bell ZW, Yamada Y, Spitz RW, Abe T, et al. Blood flow restriction training on resting blood pressure and heart rate: a meta-analysis of the available literature. J Hum Hypertens 2021. doi: 10.1038/s41371-021-00561-0
Nascimento DC, Schoenfeld BJ, Prestes J. Potential implications of blood flow restriction exercise on vascular health: a brief review. Sports Med 2020;50(1):73-81. doi: 10.1007/s40279-019-01196-5
Suga T, Okita K, Takada S, Omokawa M, Kadoguchi Yokota T, et al. Effect of multiple set on intramuscular metabolic stress during low-intensity resistance exercise with blood flow restriction. Eur J Appl Physiol 2012;112(11):3915-20. doi: 10.1007/s00421-012-2377-x
Patterson SD, Hughes L, Warmington S, et al. Blood flow restriction exercise: considerations of methodology, application, and safety. Front Physiol 2019;10:533. doi: 10.3389/fphys.2019.00533
Chisholm DM, Collis ML, Kulak LL, Davenport W, Gruber N. Physical activity readiness. B C Med J 1975;17:375-8.
Motykie GD, Zebala LP, Caprini JA, Lee CE, Arcelus JI, Reyna JJ, et al. A guide to venous thromboembolism risk factor assessment. J Thromb Thrombolysis 2000;9(3):253-62. doi: 10.1023/a:1018770712660
O'Brien A, Redley B, Wood B, Botti M, Hutchinson AF. STOPDVTs: Development and testing of a clinical assessment tool to guide nursing assessment of postoperative patients for Deep Vein Thrombosis. J Clin Nurs 2018;27(9-10):1803-11. doi: 10.1111/jocn.14329
Aboyans V, Criqui MH, Abraham P, et al. Measurement and interpretation of the ankle-brachial index: a scientific statement from the American Heart Association. Circulation 2012;126(24):2890-2909. doi: 10.1161/CIR.0b013e318276fbcb
Brown LE, Weir JP. ASEP procedures recommendation I: accurate assessment of muscular strength and power. J Exerc Physiol [Internet]. 2001[cited 2022 May 12];4(3). Available from: https://www.asep.org/asep/asep/Brown2.pdf
Laurentino GC, Ugrinowitsch C, Roschel H, et al. Strength training with blood flow restriction diminishes myostatin gene expression. Med Sci Sports Exerc. 2012; 44(3):406-12. doi: 10.1249/MSS.0b013e318233b4bc
Moriggi R Junior, Mauro HD, Dias SC, Matos JM, Urtado MB, Camarço NF, et al. Similar hypotensive responses to resistance exercise with and without blood flow restriction. Biol Sport 2015;32(4):289-94. doi: 10.5604/20831862.1163691
Muntner P, Shimbo D, Carey RM, Charleston TG, Misra S, Meyers MG, et al. Measurement of blood pressure in humans: a scientific statement from the american heart association. Hypertension 2019;73(5):e35-e66. doi: 10.1161/HYP.0000000000000087
Vischer AS, Burkard T. Principles of blood pressure measurement - current techniques, office vs ambulatory blood pressure measurement. Adv Exp Med Biol 2017;956:85-96. doi: 10.1007/5584_2016_49
Severin R, Sabbahi A, Albarrati A, Phillips SA, Arena S. Blood pressure screening by outpatient physical therapists: a call to action and clinical recommendations. Phys Ther 2020;100(6):1008-19. doi: 10.1093/ptj/pzaa034
Serdar CC, Cihan M, Yücel D, Serdar MA. Sample size, power and effect size revisited: simplified and practical approaches in pre-clinical, clinical and laboratory studies. Biochem Med 2021;31(1):010502. doi: 10.11613/BM.2021.010502
Cook NR, Cohen J, Hebert PR, Taylor JO, Hennekens CH. Implications of small reductions in diastolic blood pressure for primary prevention. Arch Intern Med 1995;155(7):701-9. https://pubmed.ncbi.nlm.nih.gov/7695458/
Strandberg TE, Pitkala K. What is the most important component of blood pressure: systolic, diastolic or pulse pressure?. Curr Opin Nephrol Hypertens 2003;12(3):293-7. doi: 10.1097/00041552-200305000-00011
Faul F, Erdfelder E, Lang A-G, Buchner A. G* Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 2007;39(2):175-91. doi: 10.3758/bf03193146
Pinto RR, Polito MD. Haemodynamic responses during resistance exercise with blood flow restriction in hypertensive subjects. Clin Physiol Funct Imaging 2016;36(5):407-13. doi: 10.1111/cpf.12245
Poton R, Polito MD. Hemodynamic response to resistance exercise with and without blood flow restriction in healthy subjects. Clin Physiol Funct Imaging 2016;36(3):231-6. doi: 10.1111/cpf.12218
Pinto RR, Karabulut M, Poton R, Polito MD. Acute resistance exercise with blood flow restriction in elderly hypertensive women: haemodynamic, rating of perceived exertion and blood lactate. Clin Physiol Funct Imaging 2018;38(1):17-24. doi: 10.1111/cpf.12376
Sprick JD, Rickards CA. Cyclical blood flow restriction resistance exercise: a potential parallel to remote ischemic preconditioning? Am J Physiol Regul Integr Comp Physiol 2017;313(5):R507-R517. doi: 10.1152/ajpregu.00112.2017
Sardeli A, Ferreira M, Santos L, Cavaglieri C, Chacon-Mikahil MJS. Cardiovascular responses during and after aerobic and strength exercises with blood flow restriction in older adults. 2021. doi: 10.1016/j.scispo.2021.04.008
May AK, Brandner CR, Warmington SA. Hemodynamic responses are reduced with aerobic compared with resistance blood flow restriction exercise. Physiol Rep 2017;5(3). doi: 10.14814/phy2.13142
Loenneke JP, Thrower AD, Balapur A, Barnes JT, Pujol TJ. Blood flow-restricted walking does not result in an accumulation of metabolites. Clin Physiol Funct Imaging 2012;32(1):80-2. doi: 10.1111/j.1475-097X.2011.01059.x
Dankel SJ, Kang M, Abe T, Loenneke JP. A meta-analysis to determine the validity of taking blood pressure using the indirect cuff method. Curr Hypertens Rep 2019;21(1):11. doi: 10.1007/s11906-019-0929-8
Araújo JP, Silva ED, Silva JC, Souza TS, Lima EO, Guerra I, Sousa MS. The acute effect of resistance exercise with blood flow restriction with hemodynamic variables on hypertensive subjects. J Hum Kinet 2014;12;43:79-85. doi: 10.2478/hukin-2014-0092
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