Prevalência de adesão medicamentosa em pacientes com doença arterial coronariana crônica
DOI:
https://doi.org/10.33233/eb.v19i2.2137Resumen
Objetivos: Avaliar a prevalência da adesão medicamentosa do paciente com doença arterial coronariana crônica e comparar os perfis clínico, socioeconômico e angiográfico de paciente aderentes e não aderentes. Métodos: Estudo observacional, transversal, prospectivo, quantitativo e descritivo, realizado de julho a outubro de 2016, em dois hospitais, sendo um público e outro privado. Forma entrevistados 130 pacientes submetidos ao procedimento de cinecoronariografia e consultados os resultados do exame. Utilizou-se o teste de Morisky-Green para mensurar a aderência a medicação. Resultados: A taxa de adesão medicamentosa foi de 26,15%, considerada baixa. Dentre as variáveis de perfis clínico, sociodemográfico e angiográfico apenas a hipertensão foi mais prevalente nos pacientes aderentes. Conclusão: Visto que a gravidade da lesão não ter tido associação direta com a adesão, sugere-se que pesquisas posteriores considerem o risco genético como fator de risco independente.
Palavras-chave: adesão í medicação, doença das coronárias, cooperação do paciente.
Citas
Dias AM, Cunha M, Santos AMM, Neves APG, Pinto AFC, Castro SA. Adesão ao regime terapêutico na doença crônica: revisão de literatura. Millenium 2011;(40)201-19.
Bezerra ASM, Lopes JL, Barros ALBL. Adesão de pacientes hipertensos ao tratamento medicamentoso. Rev Bras Enferm 2014;67(4):550-5. https://doi.org/10.1590/0034-7167.2014670408
Naderi SH, Bestwick JP, Wald DS. Adherence to drugs that prevent cardiovascular disease: meta-analysis on 376,162 patients. Am J Med 2012;125(9):882-7. https://doi.org/10.1016/j.amjmed.2011.12.013
Cesar LA, Ferreira JF, Armaganijan D, Gowdak LH, Mansur AP, Bodanese LC, et al. Diretriz de Doença Coronária Estável. Arq Bras Cardiol 2014;103(2Supl.2): 1-59.
Ben AJ, Neumann CR, Mengue SS. The Brief Medication Questionnaire and Morisky-Green Test to evaluate medication adherence. Rev Saúde Pública 2012;46(2):279-89. https://doi.org/10.1590/S0034-89102012005000013
Naderi SH, Bestwick JP, Wald DS. Adherence to drugs that prevent cardiovascular disease: meta-analysis on 376,162 patients. Am J Med 2012;125(9):882-7.e1. https://doi.org/10.1016/j.amjmed.2011.12.013
Lunelli RP, Portal VL, Esmério FG, Morais MA, Souza EM. Patients’ with coronary arterial disease’ adherence to pharmacological and non-pharmacological therapy. Acta Paul Enf. 2009;22(4):367-73. https://doi.org/10.1590/S0103-21002009000400003
Oliveira DC, Santos MVR, Gomes VR, Sarinho FW, Novaes M. Prevalência de adesão a fármacos anti-hipertensivos: registro de mundo real. Rev Bras Clin Med 2013;11(3):219-22.
Xavier HT, Izar MC, Faria Neto JR, Assad MH, Rocha VZ, Sposito AC, et al. V Diretriz Brasileira Sobre Dislipidemias e Prevenção da Aterosclerose. Arq Bras Cardiol 2013;101(4Supl).
Reis LA, Ventura AM. Fatores associados ao uso errado de medicamentos em idosos. Cad Saúde Pública 2003;19(3):717-24.
Kähkönen O, Saaranen T, Kankkunen P, Lamidi ML, Kyngäs H, Miettinen H. Predictors of adherence to treatment by patients with coronary heart disease after percutaneous coronary intervention. J Clin Nurs 2017;3. https://doi.org/10.1111/jocn.14153
Kähkönen O, Kankkunen P, Miettinen H, Lamidi ML, Saaranen T. Perceived social support following percutaneous coronary intervention is a crucial factor in patients with coronary heart disease. J Clin Nurs 2017;26(9-10):1264-80. https://doi.org/10.1111/jocn.13527
Lin JS, O'Connor EA, Evans CV, Senger CA, Rowland MG, Groom HC. Behavioral counseling to promote a healthy lifestyle for cardiovascular disease prevention in persons with cardiovascular risk factors: An updated systematic evidence review for the U.S. Preventive Services Task Force. Rockville (MD): Agency for Healthcare Research and Quality (US);2014. Report 13-05179-EF-1.
Kähkönen O, Kankkunen P, Saaranen T, Miettinen H, Kyngäs H, Lamidi ML. Motivation is a crucial factor for adherence to a healthy lifestyle among people with coronary heart disease after percutaneous coronary intervention. J Adv Nurs 2015;71(10):2364-73. https://doi.org/10.1111/jan.12708
Saeidzadeh S, Darvishpoor Kakhki A, Abed Saeedi J. Factors associated with self-care agency in patients after percutaneous coronary intervention. J Clin Nurs 2016;25(21-22):3311-16. https://doi.org/10.1111/jocn.13396
Ahmed HM, Blaha MJ, Nasir K, Jones SR, Rivera JJ, Agatston A, et al. Low-risk lifestyle, coronary calcium, cardiovascular events, and mortality: results from MESA. Am J Epidemiol 2013;178(1):12-21. https://doi.org/10.1093/aje/kws453
Toth PP. Triglyceride-rich lipoproteins as a causal factor for cardiovascular disease. Vasc Health Risk Manag 2016;12:171-83. https://doi.org/10.2147/VHRM.S104369
Natarajan P, Young R, Stitziel NO, Padmanabhan S, Baber U, Mehran R, Sartori S, et al. Polygenic risk score identifies subgroup with higher burden of atherosclerosis and greater relative benefit from statin therapy in the primary prevention setting. Circulation. 2017;135(22):2091-101. https://doi.org/10.1161/CIRCULATIONAHA.116.024436
Khera AV, Emdin CA, Drake I, Natarajan P, Bick AG, Cook NR, et al. Genetic risk, adherence to a healthy lifestyle, and coronary disease. N Engl J Med 2016;375(24):2349-58. https://doi.org/10.1056/NEJMoa1605086
Gómez-Barrado JJ, Ortiz C, Gómez-Turégano M, Gómez-Turégano P, Garcipérez-de-Vargas FJ, Sánchez-Calderón P. Lipid control in patients with coronary artery disease in a healthcare area in Cáceres (Spain): LIPICERES study. Clin Investig Arterioscler 2017;29(1):13-19. https://doi.org/10.1016/j.arteri.2016.09.003
Santo K, Chow CK, Thiagalingam A, Rogers K, Chalmers J, Redfern J. MEDication reminder APPs to improve medication adherence in Coronary Heart Disease (MedApp-CHD) Study: a randomised controlled trial protocol. BMJ Open 2017;7(10):e017540. https://doi.org/10.1093/eurheartj/ehy565.1109
Santo K, Richtering SS, Chalmers J, Thiagalingam A, Chow CK, Redfern J. Mobile phone apps to improve medication adherence: a systematic stepwise process to identify high-quality apps. JMIR Mhealth Uhealth 2016;4(4):e132. https://doi.org/10.2196/mhealth.6742
Santo K, Kirkendall S, Laba TL, Thakkar J, Webster R, Chalmers J, Chow CK, Redfern J. Interventions to improve medication adherence in coronary disease patients: A systematic review and meta-analysis of randomised controlled trials. Eur J Prev Cardiol 2016;23(10):1065-76. https://doi.org/10.1177/2047487316638501
Sadeghian S, Shams M, Alipour Z, Saadat S, Hamidian R, Shahrzad M. Application of short message service to control blood cholesterol: a field trial. BMC Med Inform Decis Mak 2017;17(1):32. https://doi.org/10.1186/s12911-017-0427-3
Peimani M, Rambod C, Omidvar M, Larijani B, Ghodssi-Ghassemabadi R, Tootee A, Esfahani EN. Effectiveness of short message service-based intervention (SMS) on self-care in type 2 diabetes: A feasibility study. Prim Care Diabetes 2016;10(4):251-8. https://doi.org/10.1016/j.pcd.2015.11.001
Bitton A, Choudhry NK, Matlin OS, Swanton K, Shrank WH. The impact of medication adherence on coronary artery disease costs and outcomes: a systematic review. Am J Med 2013;126(4):357.e7-357.e27. https://doi.org/10.1016/j.amjmed.2012.09.004
