Obesity Hypoventilation Syndrome and more effective ventilatory strategy: continuous positive airway pressure or non-invasive ventilation?
DOI:
https://doi.org/10.33233/fb.v22i5.4559Keywords:
obesity; sleep apnea, obstructive; noninvasive ventilation; continuous positive airway pressureAbstract
Considering the Obesity Hypoventilation Syndrome (OHS) as potentially treatable, it is difficult to compare clinical trials due to the different titers of non-invasive mechanical ventilation (NIV) and continuous positive airway pressure (CPAP). The objective was to carry out an integrative literature review using positive pressure as a therapeutic method. Randomized clinical trials using CPAP compared to NIV as treatment were included. The search took place in the PubMed and Web of Science databases, including studies published between 2008 and 2017, using the keywords: “Obesity Hypoventilation AND noninvasive ventilation AND nocturnal hypoventilation”; “Obesity hypoventilation AND noninvasive ventilation AND CPAP”; “Obesity Hypoventilation AND nocturnal hypoventilation AND ventilation” and manual search for other relevant articles. 4 articles were selected. Two studies comparing CPAP and bilevel. They showed similar improvement between groups. The third study compared the control group, both being efficient in relation to the CG, with improvement in PaCO2, Bic, clinical symptoms, polysomnographic parameters and side effects. The fourth study presented for Assured Medium-Volume Pressure Support (AVAPS-AE), CPAP, and Bi-Level efficacy in reducing nocturnal BP surges. Thus, a similar efficacy is observed between both strategies, and both are more effective when compared to a control group.
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