Risk factors for reintubation in the intensive care unit of a trauma hospital

Authors

DOI:

https://doi.org/10.33233/fb.v22i4.4910

Keywords:

airway extubation; risk factors; wounds and injuries

Abstract

Mechanical ventilation (MV) is a resource frequently used in the Intensive Care Unit (ICU). However, the need for reintubation after the withdrawal of ventilatory support is associated with unfavorable outcomes. The objectives of this study were to identify possible risk factors and clinical outcome of patients reintubated in the ICU of a trauma referral hospital. A prospective cohort study was performed in a period of 4 months with adult patients admitted to the ICU and who remained on MV for at least 24 hours. The sample consisted of 100 patients divided into a group of non-reintubated patients and patients who attended with the need to return to MV. 27 patients were reintubated, 18 of them reintubated within 48 hours after extubation. Age, diabetes, obesity, time from MV to extubation and respiratory rate (RR) were variables that showed a statistically significant difference between groups (p < 0.05) but could not be identified as independent risk factors for return to ventilation. Reintubation was associated with the need for tracheostomies (TQT) (p < 0.001), longer length of stay on MV (p < 0.001), prolonged ICU stay (p < 0.001) and mortality (p < 0.005). Age, presence of diabetes, obesity, longer MV and higher pre-extubation RF were the variables related to reintubation. This event was directly associated with worse outcomes such as need for TQT, greater dependence on MV, prolonged ICU stay and mortality.

Author Biographies

Polliana Oliveira Melo, FHEMIG

Fisioterapeuta residente do Programa de Residência Multiprofissional em Saúde área de concentração urgência e emergência do Hospital João XXIII da Fundação Hospitalar do Estado de Minas Gerais (FHEMIG)

Julia Alencar Renault, FHEMIG

M.Sc., Fisioterapeuta da Unidade de Terapia Intensiva do Hospital João XXIII da FHEMIG

Priscilla Cristina Ribeiro Soares, FHEMIG

Fisioterapeuta da Unidade de Terapia Intensiva do Hospital João XXIII da FHEMIG

References

Weinberg JA, Stevens LR, Goslar PW, Thompson TM, Sanford JL, Petersen SR. Risk factors for extubation failure at a level I trauma center: does the specialty of the intensivist matter? Trauma Surgery & Acute Care Open 2016;1(1):e000052. doi: 10.1136/tsaco-2016-000052

Lai CC, Chen CM, Chiang SR, Liu WL, Weng SF, Sung MI, et al. Establishing predictors for successfully planned endotracheal extubation. Medicine (Baltimore) 2016;95(41):e4852. doi: 10.1097/MD.0000000000004852

Thille AW, Richard JC, Brochard L. The decision to extubate in the intensive care unit. Am J Respir Crit Care Med 2013;187(12):1294-302. doi: 10.1164/rccm.201208-1523CI

Hsiung Lee ES, Jiann Lim DT, Taculod JM, Sahagun JT, Otero JP, Teo K, et al. Factors Associated with reintubation in an Intensive Care Unit: A prospective observational study. Indian J Crit Care Med 2017;21(3):131-7. doi: 10.4103/ijccm.IJCCM_452_16

Girard TD, Alhazzani W, Kress JP, Ouellette DR, Schmidt GA, Truwit JD, et al. An Official American Thoracic Society/American College of Chest Physicians Clinical Practice Guideline: Liberation from Mechanical Ventilation in Critically Ill Adults. Rehabilitation Protocols, Ventilator Liberation Protocols, and Cuff Leak Tests. Am J Respir Crit Care Med 2017;195(1):120-33. doi: 10.1164/rccm.201610-2075ST

Goldwasser R, Farias A, Freitas EE, Saddy F, Amado V, Okamoto VN. Desmame e interrupção da ventilação mecânica. Revista Brasileira de Terapia Intensiva 2007;19:384-92. doi: 10.1590/S0103-507X2007000300021

Artime CA, Hagberg CA. Tracheal extubation. Respir Care 2014;59(6):991-1002. doi: 10.4187/respcare.02926

Bilello JF, Davis JW, Cagle KM, Kaups KL. Predicting extubation failure in blunt trauma patients with pulmonary contusion. J Trauma Acute Care Surg 2013;75(2):229-33. doi: 10.1097/TA.0b013e3182946649

Bobbs M, Trust MD, Teixeira P, Coopwood B, Aydelotte J, Tabas I, et al. Decreasing failed extubations with the implementation of an extubation checklist. Am J Surg 2019;217(6):1072-5. doi: 10.1016/j.amjsurg.2019.02.028

Alomía D, Coral M, Ortegón S, Soto R, Muñoz V. Factores de riesgo asociados con la extubación fallida en pacientes adultos de una unidad de cuidados intensivos de la ciudad de Cali. Revista Ciencias de la Salud 2017;15(2):237-46. doi: 10.12804/revistas.urosario.edu.co/revsalud/a.5760

Maezawa S, Kudo D, Miyagawa N, Yamanouchi S, Kushimoto S. Association of body weight change and fluid balance with extubation failure in intensive care unit patients: a single-center observational study. J Intensive Care Med 2019:885066619887694. doi: 10.1177/0885066619887694

Pogorzelski GF, Silva TA, Piazza T, Lacerda TM, Spencer Netto FA, Jorge AC, et al. Epidemiology, prognostic factors, and outcome of trauma patients admitted in a Brazilian intensive care unit. Open Access Emerg Med 2018;10:81-8. doi: 10.2147/OAEM.S162695

Maggiore SM, Battilana M, Serano L, Petrini F. Ventilatory support after extubation in critically ill patients. Lancet Respir Med 2018;6(12):948-62. doi: 10.1016/S2213-2600(18)30375-8

Piriyapatsom A, Williams EC, Waak K, Ladha KS, Eikermann M, Schmidt UH. Prospective observational study of predictors of re-intubation following extubation in the surgical ICU. Respir Care 2016;61(3):306-15. doi: 10.4187/respcare.04269

Mahmood S, Alani M, Al-Thani H, Mahmood I, El-Menyar A, Latifi R. Predictors of reintubation in trauma intensive care unit: qatar experience. Oman Med J 2014;29(4):289-93. doi: 10.5001/omj.2014.75

Brown CV, Daigle JB, Foulkrod KH, Brouillette B, Clark A, Czysz C, et al. Risk factors associated with early reintubation in trauma patients: a prospective observational study. J Trauma 2011;71(1):37-41. doi: 10.1097/TA.0b013e31821e0c6e

Tu CS, Chang CH, Chang SC, Lee CS, Chang CT. A decision for predicting successful extubation of patients in Intensive Care Unit. Biomed Res Int 2018:6820975. doi: 10.1155/2018/6820975

Howie WO, Dutton RP. Implementation of an evidence-based extubation checklist to reduce extubation failure in patients with trauma: a pilot study. AANA J [Internet]. 2012 [cited 2021 Aug 8];80(3):179-84. https://pubmed.ncbi.nlm.nih.gov/22848978/

Fujii E, Fujino K, Tanaka-Mizuno S, Eguchi Y. Variation of risk factors for cause-specific reintubation: A preliminary study. Can Respir J 2018:3654251. doi: 10.1155/2018/3654251

Thille AW, Harrois A, Schortgen F, Brun-Buisson C, Brochard L. Outcomes of extubation failure in medical intensive care unit patients. Crit Care Med 2011;39(12):2612-8. doi: 10.1097/CCM.0b013e3182282a5a

Thille AW, Boissier F, Ben Ghezala H, Razazi K, Mekontso-Dessap A, Brun-Buisson C. Risk factors for and prediction by caregivers of extubation failure in ICU patients: a prospective study. Crit Care Med 2015;43(3):613-20. doi: 10.1097/CCM.0000000000000748

Miltiades AN, Gershengorn HB, Hua M, Kramer AA, Li G, Wunsch H. Cumulative probability and time to reintubation in U.S. ICUs. Crit Care Med 2017;45(5):835-42. doi: 10.1097/CCM.0000000000002327

Xie J, Cheng G, Zheng Z, Luo H, Ooi OC. To extubate or not to extubate: Risk factors for extubation failure and deterioration with further mechanical ventilation. J Card Surg 2019;34(10):1004-11. doi: 10.1111/jocs.14189

Sará-Ochoa JE, Hernández Ortíz OH, Jaimes FA. Development of a predictive model for extubation failure in weaning from mechanical ventilation: A retrospective cohort study. Trends in Anaesthesia and Critical Care 2017;17:21-6. doi: 10.1016/j.tacc.2017.10.060

Li Y, Li H, Zhang D. Comparison of T-piece and pressure support ventilation as spontaneous breathing trials in critically ill patients: a systematic review and meta-analysis. Critical Care 2020;24(1):67. doi: 10.1186/s13054-020-2764-3

Wilkinson K, Freeth H, Kelly K. 'On the Right Trach?' A review of the care received by patients who undergo tracheostomy. Br J Hosp Med (Lond) 2015;76(3):163-5. doi: 10.12968/hmed.2015.76.3.163

Saiphoklang N, Auttajaroon J. Incidence and outcome of weaning from mechanical ventilation in medical wards at Thammasat University Hospital. PLoS One 2018;13(10):e0205106. doi: 10.1371/journal.pone.0205106

Published

2021-11-02