Physical therapy in cognition deficits and functional disabilities in patients with Alzheimer's disease: an integrative review
DOI:
https://doi.org/10.33233/fb.v24i5.5296Keywords:
Alzheimer's disease, Physiotherapy, RehabilitationAbstract
Objective: To review the scientific literature and highlight the physiotherapeutic performance in cognitive deficits and functional disabilities in patients with Alzheimer's Disease (AD). Methods: An integrative literature review was carried out. The search for articles took place from September to December 2021, in the portals/electronic databases: Medline/PubMed, Physiotherapy Evidence Database (PEDro), Scientific Electronic Library Online (SciELO) and Virtual Health Library (BVS), using indexed descriptors (Alzheimer's Disease and Physical therapy). Articles published between 2011 and 2021, of the observational or intervention type, in English, Portuguese and Spanish were included. Editorials, case reports, reviews and theses/dissertations were excluded. Results: 293 articles were found, of which 8 articles were included. Physical therapy is a good treatment option for patients with AD, with aerobic exercises being the most used. Functional and dual-task exercises, memory training, balance, progressive task-oriented circuit training, and motor coordination are also mentioned in the literature. Patients who were in the initial phase of the disease when submitted to the physiotherapeutic program showed a significant reduction in neuropsychiatric disorders, in addition to greater social interaction and maintenance of functional capacity. Conclusion: In view of the results, it was evidenced that physical therapy activity contributes positively to the maintenance of functional capacity and delay of cognitive deficits in patients with AD.
References
Alzheimer’s Association. 2014 Alzheimer’s disease facts and figures. Alzheimer´s Dement. 2014;10(2):e47–92. doi: 10.1016/j.jalz.2014.02.001
Bitencourt EMB, Kuerten CMX, Budny J, Tuon T. Doença de Alzheimer: aspectos fisiopatológicos, qualidade de vida, estratégias terapêuticas da fisioterapia e biomedicina. Inova Saúde. 2019;1(48):116–29. doi: 10.18616/inova.v8i2.3573
Darby RR, Brickhouse M, Wolk DA, Dickerson BC. Effects of cognitive reserve depend on executive and semantic demands of the task. J Neurol Neurosurg Psychiatry. 2017;88(9):794–802. doi: 10.1136/jnnp-2017-315719
Alves JED. Transição demográfica, transição da estrutura etária e envelhecimento. Rev Portal Divulg [Internet]. 2014;40
Burlá C, Camarano AA, Kanso S, Fernandes D, Nunes R. Panorama prospectivo das demências no Brasil: Um enfoque demográfico. Cienc Saude Coletiva. 2013;18(10):2949–56. doi: 10.1590/S1413-81232013001000019
Prince M, Bryce R, Albanese E, Wimo A, Ribeiro W, Ferri CP. The global prevalence of dementia: A systematic review and metaanalysis. Alzheimer’s Dement. 2013;9(1):63-75. doi: 10.1016/j.jalz.2012.11.007
Kocahan S, Doǧan Z. Mechanisms of Alzheimer’s disease pathogenesis and prevention: The brain, neural pathology, N-methyl-D-Aspartate receptors, tau protein and other risk factors. Clin Psychopharmacol Neurosci. 2017;15(1):1–8. doi: 10.9758/cpn.2017.15.1.1
Brasil MC, Andrade CC. Reconfiguração de campo do familiar cuidador do portador de Alzheimer. Psicol Estud. 2013;18(4):713–23.
Maciel MG. Atividade física e funcionalidade do idoso. Motriz Rev Educ Física UNESP. 2010;1024–32. doi: 10.5016/1980-6574.2010v16n4p1024
Van Nimwegen M, Speelman AD, Smulders K, Overeem S, Borm GF, Backx FJG, et al. Design and baseline characteristics of the ParkFit study, a randomized controlled trial evaluating the effectiveness of a multifaceted behavioral program to increase physical activity in Parkinson patients. BMC Neurol. 2010;10. doi: 10.1186/1471-2377-10-70
Ilha S, Backes DS, Santos SSC, Gautério-Abreu DP, Silva BT, Pelzer MT. Alzheimer’s disease in elderly/family: Difficulties experienced and care strategies. Esc Anna Nery - Rev Enferm. 2016;20(1):138–46. doi: 10.5935/1414-8145.20160019
Zidan M, Arcoverde C, de Araújo NB, Vasques P, Rios A, Laks J, et al. Alterações motoras e funcionais em diferentes estágios da doença de Alzheimer. Rev Psiquiatr Clin. 2012;39(5):161–5. doi: 10.1590/S0101-60832012000500003
Vidoni ED, Watts AS, Burns JM, Greer CS, Graves RS, Van Sciver A, et al. Feasibility of a Memory Clinic-Based physical activity prescription program based on memory clinic. J Alzheimers Dis. 2018;53(1). doi: 10.3233/JAD-160158
Morris JK, Vidoni ED, Johnson DK, Van Sciver A, Mahnken JD, Honea RA, et al. Aerobic exercise for Alzheimer’s disease: A randomized controlled pilot trial. PLoS One. 2017;12(2):1–14. doi: 10.1371/journal.pone.0170547
Vega-Ramírez FA, López-Liria R, Granados-Gámez G, Aguilar-Parra JM, Padilla-Góngora D. Analysis of home-based rehabilitation in patients with motor impairment in primary care: A prospective observational study. BMC Geriatr. 2017;17(1):4–11. doi: 10.1186/s12877-017-0526-0
Shehab M, Abd El-Kader, Al-Jiffri OH. Aerobic exercise improves quality of life, psychological well-being and systemic inflammation in subjects with Alzheimer’s disease. Afr Health Sci. 2016;16(4):1045–55. doi: 10.4314/ahs.v16i4.22
Vidoni ED, Johnson DK, Morris JK, Van Sciver A, Greer CS, Billinger SA, et al. Dose-response of aerobic exercise on cognition: A community-based, pilot randomized controlled trial. PLoS One. 2015;10(7):1–13. doi: 10.1371/journal.pone.0131647
Nascimento CMC, Teixeira CVL, Gobbi LTB, Gobbi S, Stella F. A controlled clinical trial on the effects of exercise on neuropsychiatric disorders and instrumental activities in women with Alzheimer’s disease. Brazilian J Phys Ther. 2012;16(3):197–204. doi: 10.1590/S1413-35552012005000017
Canonici, AP, Andrade LPD, Gobbi, S, Santos‐Galduroz RF, Gobbi, LTB, Stella F. Functional dependence and caregiver burden in Alzheimer's disease: a controlled trial on the benefits of motor intervention. Psychogeriatrics 2012;12(3):186-92. doi: 10.1111/j.1479-8301.2012.00407
Gbiri CAO, Amusa BF. Progressive task‐oriented circuit training for cognition, physical functioning and societal participation in individuals with dementia. Physiotherapy Research International 2020;25(4):e1866. doi: 10.1002/pri.1866
Weller J, Budson A. Current understanding of Alzheimer’s disease diagnosis and treatment. F1000 Research. 2018;7(0):1–9. doi: 10.12688/f1000research.14506.1
Lourenco MV, Frozza RL, Freitas GB, Zhang H, Kincheski GC, Ribeiro FC, et al. Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models. Nat Med. 2019;25:165-75. doi: 10.1038/s41591-018-0275-4
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Copyright (c) 2023 Francisco Valter Miranda Silva, Francisco Felipe Cardozo Rabelo, Rosana Iorio Ferreira, Jacqueline Aguiar da Silva, Davy Deusdeth Timbó Magalhães Sobrinho, Lindolfo Jorge Magalhães Silva, Jéssica Pereira Guedes, Letícia Ellen Correia Costa, Luciana Silva Lima, Paula Pessoa de Brito Nunes
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