Correlations between cognitive function, functional independence and risk fall in elderly people with Alzheimer’s disease

Authors

DOI:

https://doi.org/10.33233/fb.v24i4.5357

Keywords:

Alzheimer Disease, Aged, Cognition, Functional Status, Accidental Falls

Abstract

Objective: To correlate the level of cognitive function, the level of functional independence and the risk of falls in elderly people with Alzheimer's dementia (AD). Methods: This is a cross-sectional, quantitative, descriptive study, of the case series type, with 20 elderly people with a clinical diagnosis of AD. Anamnesis was applied through an evaluation form with personal, clinical and treatment data; the Mini Mental State Examination (MMEM) to assess cognitive function; the Functional Independence Measure (FIM) to assess the performance of the elderly in the motor and cognitive/social domains; and the Timed Up and Go (TUG) test, developed to assess the risk of falling in the elderly. To analyze the correlation between cognitive level and level of functional independence and cognitive level and risk of falls, Spearman's correlation index was calculated. Results: There was a strong correlation between MMSE and FIM scores (r=0.831; p < 0.001), between MMSE and TUG scores (r= -0.933; p < 0.001) and between FIM scores and TUG (r= -0.857; p < 0.001). There was also a strong correlation between AD stage and MMSE score (r=-0.946; p < 0.001), total FIM score (r=-0.904; p < 0.001); and, the TUG score (r=0.942; p < 0.001). Conclusion: There is a correlation between cognitive function, level of functional independence and risk of falling in elderly people with AD, and as the condition evolves in severity, there is a worsening of cognitive function, reduced functional autonomy and increased risk of falls.

Author Biography

DominiqueDominique Babini Albuquerque Cavalcanti, UNINASSAU

Fisioterapeuta, Doutora em Saúde da Criança e do Adolescente (UFPE), Mestra em Educação (USP), Especialista em Fisioterapia Hospitalar, Especialista em Saúde Pública e Vigilância Sanitária, Centro Universitário Maurício de Nassau Paulista (UNINASSAU - Campus Paulista), Paulista, PE; Universidade Salgado de Oliveira (UNIVERSO - Campus Recife), Recife, PE; Hospital Otávio de Freitas (HOF – Secretaria de Saúde Estadual/PE), Recife, PE, Brasil

References

Ballard C, Gauthier S, Corbett A, Brayne C, Aarsland D, Jones E. Alzheimer’s disease. Lancet. 2011;377(9770):1019-31. doi: 10.1016/S0140-6736(10)61349-9

Silva MVF, Loures CMG, Alves LCV, Borges KBGB, Carvalho MG. Alzheimer’s disease: risk factors and potentially protective measures. J Biomed Sci. 2019;26(33). doi: 10.1186/s12929-019-0524-y

Shinohara M, Sato N, Shimamura M, Kurinami H, Hamasaki T, Chatterjee A, et al. Possible modification of Alzheimer's disease by statins in midlife: interactions with genetic and non-genetic risk factors. Front Aging Neurosci. 2014;6(71). doi: 10.3389/fnagi.2014.00071

Knopman DS, DeKosky ST, Cummings JL, Chui H, Corey-Bloom J, Small GW, et al. Practice parameter: diagnosis of dementia (na evidence-based review). Report of the quality standards subcommittee of the American Academy of Neurology. Neurology. 2001;56(9):1143-53. doi: 10.1212/wnl.56.9.1143

Bottino CMC, Carvalho IAM, Alvarez ANMA, Avila R, Zukauskas PR, Bustamante SEZ, et al. Reabilitação cognitiva em pacientes com Doença de Alzheimer. Arq Neuro-Psiquiatr. 2002;60(1). doi: 10.1590/S0004-282X2002000100013

Antunes HK, Santos RF, Cassilhas R, Santos R, Bueno OFA, Mello MT. Exercício físico e função cognitiva. Rev Bras Med Esporte. 2006;12:108-14. doi: 10.1590/S1517-86922006000200011

Lourenço RA, Veras RP. Mini-Exame do Estado Mental: características psicométricas em idosos ambulatoriais. Rev Saúde Publica. 2006;40(4):712-9. doi: 10.1590/S0034-89102006000500023

Shubert TE, Schrodt LA, Mercer VS, Busby-Whitehead, Giuliani CA. Are scores on balance screening tests associated with mobility in older adults? J Geriatr Phys Ther [Internet]. 2006 [citado 2022 jan 12];29:33-9. Disponível em: https://pubmed.ncbi.nlm.nih.gov/16630375/

Talmelli LFS, Gratão ACM, Kusumota L, Rodrigues RAP. Nível de independência funcional e déficit cognitivo em idosos com doença de Alzheimer. Rev. Esc. Enferm. USP. 2010;44(4). doi: 10.1590/S0080-62342010000400011

Christofoletti G, Oliani MM, Gobbi LTB, Gobbi S, Stella F. Risco de quedas em idosos com doenças de Parkinson e demência de Alzheimer: um estudo transversal. Rev Bras Fisioter 2006;10(4):429-33. doi: 10.1590/S1413-35552006000400011

Shaw F. Falls in older people with dementia. Geriatrics & Aging. 2003;6(7):37-40.

Suh GH, Ju YS, Yeon BK, Shah A. A longitudinal study of Alzheimer’s disease: rates of cognitive and functional decline. Int J Geriatr Psychiatry. 2004;19:817-24. doi: 10.1002/gps.1168

Shiau M, Yu L, Yuan H, Lin J, Liu C. Functional performance of Alzheimer's disease and vascular dementia in southern Taiwan. Kaohsiung J Med Sci. 2006;22:437-46. doi: 10.1016/S1607-551X(09)70335-3

Ismail SMT, Antunes MD, Moreira CR, Nascimento Junior JRA, Oliveira DV. Risco de queda em idosos institucionalizados com Doença de Alzheimer. Revista Inspirar. 2019;19(2).

Bertazone TMA, Ducatti M, Camargo HPM, Batista JMF, Marques S. Ações multidisciplinares/interdisciplinares no cuidado ao idoso com Doença de Alzheimer. Rev Rene [Internet]. 2016 [citado 2023 jan 15];17(1):144-53. Disponível em: http://periodicos.ufc.br/rene/article/view/2633

Marra TA, Pereira LSM, Faria CDCM, Pereir DS, Martins MAA, Tirada MGA. Avaliação das atividades de vida diária de idosos com diferentes níveis de demência. Rev Bras Fisioter. 2007;11:267-73. doi: 10.1590/S1413-35552007000400005

Cader SA, Vale RG, Castro JC, Bacelar SC, Biehl C, Gomes MCVG et al. Inspiratory muscle training improves maximal inspiratory pressure and may assist weaning in older intubated patients: a randomised trial. J Physiother. 2010;56:171-7. doi: 10.1016/S1836-9553(10)70022-9

Lautenschlager NT, Cox KL, Flicker L, Foster JK, Van Bockxmeer FM, Xiao J, et al. Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial. JAMA. 2008;300:1027-37. doi: 10.1001/jama.300.9.1027

Torres A, Fratiglioni L, Guo Z, Viitanen M, Von Strauss E, Winbla B. Dementia is the major cause of functional dependence in the elderly: 3- year follow-up data from population-based study. Ame J Public Health. 1998;88:1452-6. doi: 10.2105/ajph.88.10.1452

Anaka EH, Santos PF, Silva MF, Botelho PFFB, Silva P, Rodrigues NC, et al. The effect of supervised and home based exercises on balance in elderly subjects: a randomized controlled trial to prevent falls. Rev Bras Geriatric Gerontol. 2016;19(3):383-397. doi: 10.1590/1809-98232016019.150027

Speciali DS, Vasconcelos TB, Ferreira WS, Alonso AC. Abordagem fisioterapêutica voltada para aspectos cognitivos e motores da Doença de Alzheimer. Neuroc Psicol. 2016;12(1):73-86.

Miranda HAA. Correlação entre funcionalidade, mobilidade e risco de quedas em idosos com Doença de Alzheimer [Dissertação]. Brasília: Universidade de Brasília; 2014.

Woellner SS, Araújo AGS, Risso PR, Hoepfer Junior H. Estudo comparativo da mobilidade orientada pelo desempenho em idosos com e sem doença de Alzheimer. Rev Bras Med [Internet]. 2012 [citado 2022 nov 10];69(11). Disponível em: https://pesquisa.bvsalud.org/portal/resource/pt/lil-663160

Santos LCCS, Lira M. Correlação entre função cognitiva e capacidade funcional nos indivíduos com Doença de Alzheimer. Cadernos de Pós-Graduação em Distúrbios do Desenvolvimento [Internet]. 2012 [citado 2023 jan 19];12(2)36-45. Disponível em: https://editorarevistas.mackenzie.br/index.php/cpgdd/article/view/11220

Borges LL, Albuquerque CR, Garcia PA. O impacto do declínio cognitivo, da capacidade funcional e da mobilidade de idosos com doença de Alzheimer na sobrecarga dos cuidadores. Fisioter. Pesqui. 2009;16(3):246-51. doi: 10.1590/S1809-29502009000300010

Zidan M, Arcoverde C, Araújo NB, Vasques P, Rios A, Laks J, et al. Motor and functional changes in different stages of Alzheimer's disease. Rev Psiquiatr Clín [Internet]. 2012[citado 2023 jan 23];39(5):161-5. Disponível em: https://www.scielo.br/j/rpc/a/qJgc5cdK6PCXfKgSM9dFrMk/?format=pdf&lang=en

Published

2023-09-06