Exercise tolerance on post-repair tetralogy of Fallot: a systematic review with meta-analysis
Review - e235576 - Published 2024 March 18
DOI:
https://doi.org/10.33233/rbfex.v23i1.5576Keywords:
Fallot tetralogy, physical exercise, congenital heart disease, exercise physiologyAbstract
Introduction: Tetralogy of Fallot (TOF) is the most prevalent cyanotic congenital heart disease, representing around 10 to 15% of congenital heart diseases. The treatment of TOF is done through the surgical repair of cardiac anatomic anomalies. However, even after complete correction in TOF, there is a difference in cardiorespiratory capacity between people with corrected TOF and their healthy peers. Objective: To compare the cardiorespiratory capacity of people with and without TOF through specialized literature. Methodology: This is a systematic review with meta-analysis registered in Prospero under the number: CRD42020205264. Searches were carried out in the Medline databases via PubMed, PEDro and SciELO by crossing the Health Sciences Descriptors (DeCS) and Medical Subject Headings (Mesh): ((Fallot Tetralogy) AND (exercise)), without temporal or linguistic restrictions. Results: Seven studies were selected for the qualitative synthesis, 3 were included for the meta-analysis where there was attenuation of maximum oxygen consumption (-6.56 [95%CI: -11.24; -1.89] and heart rate maximum (-21.47 [CI95%: -40.09; -2.85]) of people with corrected TOF compared to their healthy peers. Conclusion: Individuals with TOF, even after surgical repair, have lower tolerance during specific exercise tests.
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